Alternating Early Afterdepolarizations Underlying Bradycardia-Dependent Macroscopic T Wave and Discordant Mechanical Alternans
Sign Up to like & getrecommendations! Published in 2023 at "Circulation: Arrhythmia and Electrophysiology"
DOI: 10.1161/circep.122.011453
Abstract: Background: Macroscopic T wave alternans (macro-TWA) often heralds the onset of Torsades de Pointes in patients with QT prolongation. However, the mechanisms underlying macro-TWA remain unclear. We examined the cellular and ionic basis for macro-TWA… read more here.
Keywords: alternating early; mechanical alternans; macroscopic wave; early afterdepolarizations ... See more keywords
Prediction of the mechanical response of cardiac alternans by using an electromechanical model of human ventricular myocytes
Sign Up to like & getrecommendations! Published in 2019 at "BioMedical Engineering OnLine"
DOI: 10.1186/s12938-019-0690-x
Abstract: PurposeAlthough the quantitative analysis of electromechanical alternans is important, previous studies have focused on electrical alternans, and there is a lack quantitative analysis of mechanical alternans at the subcellular level according to various basic cycle… read more here.
Keywords: model human; ventricular myocytes; tension; human ventricular ... See more keywords