Mechanical competition triggered by innate immune signaling drives the collective extrusion of bacterially infected epithelial cells.
Sign Up to like & getrecommendations! Published in 2021 at "Developmental cell"
DOI: 10.1016/j.devcel.2021.01.012
Abstract: Intracellular pathogens alter their host cells' mechanics to promote dissemination through tissues. Conversely, host cells may respond to the presence of pathogens by altering their mechanics to limit infection. Here, we monitored epithelial cell monolayers… read more here.
Keywords: mechanical competition; immune signaling; innate immune; cell ... See more keywords