LAUSR

Stiffness‐Controlled Thermoresponsive Hydrogels for Cell Harvesting with Sustained Mechanical Memory

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0 Published in 2017 at "Advanced Healthcare Materials"

DOI: 10.1002/adhm.201601152

Abstract: Most mechanobiological investigations focused on in situ mechanical regulation of cells on stiffness-controlled substrates with few downstream applications, as it is still challenging to harvest and expand mechanically primed cells by enzymatic digestion (e.g., trypsin)… read more here.

Keywords: cell harvesting; mechanical memory; thermoresponsive hydrogels; stiffness controlled ... See more keywords

Novel strategy to improve hepatocyte differentiation stability through synchronized behavior‐driven mechanical memory of iPSCs

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1 Published in 2022 at "Biotechnology and Bioengineering"

DOI: 10.1002/bit.28285

Abstract: Cellular homeostasis is assumed to be regulated by the coordination of dynamic behaviors. Lack of efficient methods for synchronizing large quantities of cells makes studying cell culture strategies for bioprocess development challenging. Here, we demonstrate… read more here.

Keywords: hepatocyte differentiation; behavior driven; mechanical memory; differentiation ... See more keywords

Effect of curing agents n‐octylamine and m‐xylene diamine on the mechanical and memory properties of E51 epoxy resin

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0 Published in 2024 at "Polymers for Advanced Technologies"

DOI: 10.1002/pat.6428

Abstract: The effects of curing agents n‐octylamine (OA) and m‐xylene diamine (MXDA) on the mechanical and memory properties of E51 epoxy resin (EP) are investigated in this work. The curing mechanism and thermal stability of OA… read more here.

Keywords: memory; xylene diamine; octylamine xylene; curing agents ... See more keywords

Mechanical memory based biofabrication of hierarchical elastic cardiac tissue

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0 Published in 2024 at "Biofabrication"

DOI: 10.1088/1758-5090/ad89fd

Abstract: Mimicking the multilayered, anisotropic, elastic structure of cardiac tissues for controlled guidiance of 3D cellular orientation is essential in designing bionic scaffolds for cardiac tissue biofabrication. Here, a hierarchically organized, anisotropic, wavy and conductive polycaprolactone/Au… read more here.

Keywords: cardiac tissue; memory based; mechanical memory; tissue ... See more keywords

Extracellular Matrix Stiffness Conditions Glioblastoma Cells for Long-term Migration: Mechanical Memory as a Driver of Invasion and Recurrence in Glioblastoma.

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0 Published in 2025 at "Neuro-oncology"

DOI: 10.1093/neuonc/noaf205

Abstract: Extracellular matrix (ECM) stiffening correlates with tumor invasion in various cancer types, including glioblastoma (GBM). Increased matrix stiffness promotes a migratory phenotype through dysregulation of cell-ECM bidirectional communication. Exposure to stiffer environments is sensed by… read more here.

Keywords: glioblastoma; mechanical memory; invasion; matrix stiffness ... See more keywords