Posterior Insular GABA Levels Inversely Correlate with the Intensity of Experimental Mechanical Pain in Healthy Subjects
Sign Up to like & getrecommendations! Published in 2018 at "Neuroscience"
DOI: 10.1016/j.neuroscience.2017.09.043
Abstract: This study aimed to investigate the relation of GABA and glutamate levels in the posterior insula and mechanical pain sensitivity in healthy subjects. Nineteen healthy female individuals underwent single voxel magnetic resonance spectroscopy (MRS) at… read more here.
Keywords: posterior insula; mechanical pain; gaba levels; healthy subjects ... See more keywords
Tmem45b is essential for inflammation- and tissue injury–induced mechanical pain hypersensitivity
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2121989119
Abstract: Significance Persistent pain hypersensitivity associated with inflammation, surgery, trauma, and nerve injury interferes with physical and mental activities and impairs quality of life. Herein, we showed that the chemical ablation of isolectin B4-binding (IB4+) afferents… read more here.
Keywords: inflammation; mechanical pain; pain; pain hypersensitivity ... See more keywords
Influence of genetic polymorphisms on mechanical pain sensitivity and endogenous pain modulation of trigeminal and spinal areas.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of oral rehabilitation"
DOI: 10.1111/joor.13384
Abstract: BACKGROUND Previous evidence indicates significant association between genetic polymorphisms and phenotypes related to pain sensitivity in patients with temporomandibular disorders (TMD). Despite the important advances in cataloging diverse factors such as sleep disorders, anxiety and… read more here.
Keywords: pain sensitivity; genetic polymorphisms; mechanical pain; pain ... See more keywords
An ultrafast system for signaling mechanical pain in human skin
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DOI: 10.1126/sciadv.aaw1297
Abstract: Pain can be signaled as fast as touch in human peripheral nerves. The canonical view is that touch is signaled by fast-conducting, thickly myelinated afferents, whereas pain is signaled by slow-conducting, thinly myelinated (“fast” pain)… read more here.
Keywords: myelinated afferents; mechanical pain; skin; thickly myelinated ... See more keywords
Neurodynamic Treatment Promotes Mechanical Pain Modulation in Sensory Neurons and Nerve Regeneration in Rats
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DOI: 10.3390/biomedicines10061296
Abstract: Background: Somatic nerve injuries are a rising problem leading to disability associated with neuropathic pain commonly reported as mechanical allodynia (MA) and hyperalgesia. These symptoms are strongly dependent on specific processes in the dorsal root… read more here.
Keywords: neurodynamic treatment; nerve regeneration; pain; mechanical pain ... See more keywords