Cardiac Fibrotic Remodeling on a Chip with Dynamic Mechanical Stimulation.
Sign Up to like & getrecommendations! Published in 2019 at "Advanced healthcare materials"
DOI: 10.1002/adhm.201801146
Abstract: Cardiac tissue is characterized by being dynamic and contractile, imparting the important role of biomechanical cues in the regulation of normal physiological activity or pathological remodeling. However, the dynamic mechanical tension ability also varies due… read more here.
Keywords: cardiac fibrotic; phenotypic transition; dynamic mechanical; cfs ... See more keywords
Mimicking Native Heart Tissue Physiology and Pathology in Silk Fibroin Constructs through a Perfusion‐Based Dynamic Mechanical Stimulation Microdevice
Sign Up to like & getrecommendations! Published in 2021 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202101678
Abstract: In vitro cardiomyocyte (CM) maturation is an imperative step to replicate native heart tissue‐like structures as cardiac tissue grafts or as drug screening platforms. CMs are known to interpret biophysical cues such as stiffness, topography,… read more here.
Keywords: mechanical stimulation; tissue; physiology; pathology ... See more keywords
Segmental bone replacement via patient‐specific, three‐dimensional printed bioresorbable graft substitutes and their use as templates for the culture of mesenchymal stem cells under mechanical stimulation at various frequencies
Sign Up to like & getrecommendations! Published in 2018 at "Biotechnology and Bioengineering"
DOI: 10.1002/bit.26780
Abstract: The treatment of large segmental bone defects remains a challenge as infection, delayed union, and nonunion are common postoperative complications. A three‐dimensional printed bioresorbable and physiologically load‐sustaining graft substitute was developed to mimic native bone… read more here.
Keywords: graft; tissue; segmental bone; bone ... See more keywords
Biomimetic Graphene/Spongin Scaffolds for Improved Osteoblasts Bioactivity Via Dynamic Mechanical Stimulation.
Sign Up to like & getrecommendations! Published in 2021 at "Macromolecular bioscience"
DOI: 10.1002/mabi.202100311
Abstract: Biomimetics offers excellent prospects for design a novel generation of improved biomaterials. Here we explore the controlled integration of graphene oxide (GO) derivatives with a 3D marine spongin (MS) network to nanoengineer novel smart bio-based… read more here.
Keywords: bioactivity; graphene; mechanical stimulation; biomimetic graphene ... See more keywords
In Vitro 3D Mechanical Stimulation to Tendon-Derived Stem Cells by Bioreactor.
Sign Up to like & getrecommendations! Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/7651_2021_432
Abstract: Bioreactors can offer an advanced platform to provide conditions that mimic the native microenvironment, which can also provide stretching environment for mechanobiology research. Tendon-derived stem cells (TDSCs) are a type of mechanosensitive and multipotent cells,… read more here.
Keywords: stimulation; derived stem; mechanical stimulation; tendon derived ... See more keywords
Why the impact of mechanical stimuli on stem cells remains a challenge
Sign Up to like & getrecommendations! Published in 2018 at "Cellular and Molecular Life Sciences"
DOI: 10.1007/s00018-018-2830-z
Abstract: Mechanical stimulation affects growth and differentiation of stem cells. This may be used to guide lineage-specific cell fate decisions and therefore opens fascinating opportunities for stem cell biology and regenerative medicine. Several studies demonstrated functional… read more here.
Keywords: stimuli stem; mechanical stimuli; mechanical stimulation; stem ... See more keywords
Synergistic effects of mechanical stimulation and crimped topography to stimulate natural collagen development for tendon engineering.
Sign Up to like & getrecommendations! Published in 2022 at "Acta biomaterialia"
DOI: 10.1016/j.actbio.2022.04.026
Abstract: Suitable scaffold structures and mechanical loading are essential for functional tendon engineering. However, the bipolar fibril structure of native tendon collagen is yet to be recaptured in engineered tendons. This study compared the development of… read more here.
Keywords: topography; tendon; mechanical stimulation; collagen ... See more keywords
Mechanical stimulation of cervical vertebrae modulates the discharge activity of ventral tegmental area neurons and dopamine release in the nucleus accumbens
Sign Up to like & getrecommendations! Published in 2020 at "Brain stimulation"
DOI: 10.1016/j.brs.2019.11.012
Abstract: Background: Growing evidence suggests that mechanical stimulation modulates substrates in the supraspinal central nervous system (CNS) outside the canonical somatosensory circuits. Objective/Methods: We evaluate mechanical stimulation applied to the cervical spine at the C7-T1 level… read more here.
Keywords: tegmental area; stimulation; ventral tegmental; mechanical stimulation ... See more keywords
Enhanced bone healing in porous Ti implanted rabbit combining bioactive modification and mechanical stimulation.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the mechanical behavior of biomedical materials"
DOI: 10.1016/j.jmbbm.2018.06.042
Abstract: To improve the bone healing efficiency of porous titanium implants, desired biological properties of implants are mandatory, involving bioactivity, osteoconductivity, osteoinductivity and a stable environment. In this study, bare porous titanium (abbr. pTi) with the… read more here.
Keywords: bone healing; bone; hap pti; mechanical stimulation ... See more keywords
Thigmostimulation alters anatomical and biomechanical properties of bioenergy sorghum stems.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the mechanical behavior of biomedical materials"
DOI: 10.1016/j.jmbbm.2022.105090
Abstract: Sorghum [Sorghum bicolor (L.) Moench] is a tropical grass that can be used as a bioenergy crop but commonly suffers from stem structural failure (lodging) when exposed to mechanical stimuli, such as rain and wind.… read more here.
Keywords: thigmostimulation alters; anatomical biomechanical; mechanical stimulation; alters anatomical ... See more keywords
Mechanical stimulation affects growth dynamics, IAA content and activity of POD and IAA oxidase in Petunia x atkinsiana
Sign Up to like & getrecommendations! Published in 2020 at "Scientia Horticulturae"
DOI: 10.1016/j.scienta.2020.109661
Abstract: Abstract Ornamental plants are bred and purchased for their aesthetical features such as colorful flowers and leaves, as well as compact and elegant stature. Petunia is one of the most popular bedding plants for urban… read more here.
Keywords: affects growth; petunia atkinsiana; growth dynamics; mechanical stimulation ... See more keywords