Progressive Pulmonary Fibrosis Is Caused by Elevated Mechanical Tension on Alveolar Stem Cells
Sign Up to like & getrecommendations! Published in 2020 at "Cell"
DOI: 10.1016/j.cell.2019.11.027
Abstract: Fibrosis can develop in most organs and causes organ failure. The most common type of lung fibrosis is known as idiopathic pulmonary fibrosis, in which fibrosis starts at the lung periphery and then progresses toward… read more here.
Keywords: elevated mechanical; fibrosis; lung fibrosis; mechanical tension ... See more keywords
Digital Wire Analyzer of Mechanical Tension, Electrical Continuity, and Isolation
Sign Up to like & getrecommendations! Published in 2022 at "IEEE Transactions on Instrumentation and Measurement"
DOI: 10.1109/tim.2022.3214606
Abstract: A digital instrument that allows the measurement of the mechanical tension of an array of wires of known length and density, and the testing of their electrical continuity and isolation, has been developed. The instrument… read more here.
Keywords: mechanical tension; digital wire; tension; wire ... See more keywords
Mechanical tension mobilizes Lgr6+ epidermal stem cells to drive skin growth
Sign Up to like & getrecommendations! Published in 2022 at "Science Advances"
DOI: 10.1126/sciadv.abl8698
Abstract: Uniquely among mammalian organs, skin is capable of marked size change in adults, yet the mechanisms underlying this notable capacity are unclear. Here, we use a system of controlled tissue expansion in mice to uncover… read more here.
Keywords: growth; stem cells; mechanical tension; skin growth ... See more keywords
RNA-Sequence Reveals the Regulatory Mechanism of miR-149 on Osteoblast Skeleton under Mechanical Tension
Sign Up to like & getrecommendations! Published in 2022 at "Stem Cells International"
DOI: 10.1155/2022/9640878
Abstract: Objective Based on RNA-sequencing (RNA-seq), the regulation of miRNAs differentially expressed in dental, periodontal, and alveolar bone tissue of orthodontic tree shrews on osteoblast skeleton under tension was investigated. Methods Tree shrews were used to… read more here.
Keywords: mechanical tension; tree shrews; mir 149; group ... See more keywords
Preferential recruitment and stabilization of Myosin II at compartment boundaries in Drosophila
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Cell Science"
DOI: 10.1242/jcs.260447
Abstract: ABSTRACT The regulation of mechanical tension exerted at cell junctions guides cell behavior during tissue formation and homeostasis. Cell junctions along compartment boundaries, which are lineage restrictions separating cells with different fates and functions within… read more here.
Keywords: cell junctions; cell; mechanical tension; compartment boundaries ... See more keywords
Osteocytes Enhance Osteogenesis by Autophagy-Mediated FGF23 Secretion Under Mechanical Tension
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2021.782736
Abstract: Mechanical stimuli control cell behaviors that are crucial for bone tissue repair. Osteocytes sense extracellular mechanical stimuli then convert them into biochemical signals to harmonize bone remodeling. However, the mechanisms underlying this process remain unclear.… read more here.
Keywords: mechanical tension; autophagy mediated; fgf23 secretion; osteogenesis ... See more keywords
Polycystin-2 mediates mechanical tension-induced osteogenic differentiation of human adipose-derived stem cells by activating transcriptional co-activator with PDZ-binding motif
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2022.917510
Abstract: Human adipose-derived stem cells (hASCs) have multi-directional differentiation potential including osteogenic differentiation. Mechanical stimulation is thought to be a key regulator of bone remodeling and has been proved to promote osteogenic differentiation of mesenchymal stem… read more here.
Keywords: mechanical tension; tension induced; osteogenic differentiation; tension ... See more keywords