Fracture mechanics based fatigue life prediction for a weld toe crack under constant and variable amplitude random block loading—Modeling and uncertainty estimation
Sign Up to like & getrecommendations! Published in 2021 at "Engineering Fracture Mechanics"
DOI: 10.1016/j.engfracmech.2020.107487
Abstract: Abstract Propagation of weld toe cracks under cyclic loading is often predicted using fracture mechanics. In as welded condition, most of the propagation life is spent as a short crack, which is known to behave… read more here.
Keywords: weld toe; mechanics based; fracture mechanics; mechanics ... See more keywords
Damage mechanics based failure prediction for structures under seismic action
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Constructional Steel Research"
DOI: 10.1016/j.jcsr.2020.106264
Abstract: Abstract In this paper, a damage mechanics based failure criterion for seismic resistant structures is presented. The utilised innovative damage model serves to predict ductile material failure in terms of crack initiation and is suitable… read more here.
Keywords: mechanics based; damage mechanics; based failure; damage ... See more keywords
A Quantum Mechanics-Based Method to Predict Intramolecular Hydrogen Bond Formation Reflecting P-glycoprotein Recognition.
Sign Up to like & getrecommendations! Published in 2023 at "ACS medicinal chemistry letters"
DOI: 10.1021/acsmedchemlett.2c00427
Abstract: Passive membrane permeability and an active transport process are key determinants for penetrating the blood-brain barrier. P-glycoprotein (P-gp), a well-known transporter, serves as the primary gatekeeper, having broad substrate specificity. A strategy to increase passive… read more here.
Keywords: recognition; intramolecular hydrogen; quantum mechanics; based method ... See more keywords
Machine Learning for Fast, Quantum Mechanics-Based Approximation of Drug Lipophilicity
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DOI: 10.1021/acsomega.2c05607
Abstract: Lipophilicity, as measured by the partition coefficient between octanol and water (log P), is a key parameter in early drug discovery research. However, measuring log P experimentally is difficult for specific compounds and log P… read more here.
Keywords: machine learning; lipophilicity; quantum mechanics; mechanics based ... See more keywords
Statistical Mechanics-Based Schrödinger Treatment of Gravity
Sign Up to like & getrecommendations! Published in 2019 at "Entropy"
DOI: 10.3390/e21070682
Abstract: The entropic gravity conception proposes that what has been traditionally interpreted as unobserved dark matter might be merely the product of quantum effects. These effects would produce a novel sort of positive energy that translates… read more here.
Keywords: mechanics based; mechanics; statistical mechanics; gravity ... See more keywords