A cellular automaton based on plasma membrane turnover accurately recapitulates cell mechanics during epithelial scattering.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of theoretical biology"
DOI: 10.1016/j.jtbi.2017.06.021
Abstract: Epithelial cells can be triggered to actively detach from epithelial tissues and become solitary, migratory and invasive. This process occurs repeatedly in development, where it is termed epithelial-mesenchymal transition (EMT), and can be recapitulated as… read more here.
Keywords: cellular automaton; cell; mechanics epithelial; epithelial scattering ... See more keywords
Mechanics of epithelial tissue formation.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of theoretical biology"
DOI: 10.1016/j.jtbi.2018.06.002
Abstract: A key process in the life of any multicellular organism is its development from a single egg into a full grown adult. The first step in this process often consists of forming a tissue layer… read more here.
Keywords: tissue formation; mechanics epithelial; tissue; biology ... See more keywords
Unbuckling Mechanics of Epithelial Monolayers under Compression.
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DOI: 10.1103/physrevlett.134.118402
Abstract: When cell sheets fold during development, their apical or basal surfaces constrict and cell shapes approach the geometric singularity in which these surfaces vanish. Here, we reveal the mechanical consequences of this geometric singularity for… read more here.
Keywords: mechanics epithelial; mechanics; epithelial monolayers; compression ... See more keywords