Mechanism of activation and the rewired network: New drug design concepts.
Sign Up to like & getrecommendations! Published in 2021 at "Medicinal research reviews"
DOI: 10.1002/med.21863
Abstract: Precision oncology benefits from effective early phase drug discovery decisions. Recently, drugging inactive protein conformations has shown impressive successes, raising the cardinal questions of which targets can profit and what are the principles of the… read more here.
Keywords: protein; mechanism activation; network; mechanism ... See more keywords
A Mechanism for the Activation of the Influenza Virus Transcriptase
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Cell"
DOI: 10.1016/j.molcel.2018.10.005
Abstract: (Molecular Cell 70, 1101–1110.e1–e4; June 21, 2018) In the originally published article, one of the PDB ID numbers shown in the Key Resources Table and in the STAR Methods under Data and Software Availability was… read more here.
Keywords: mechanism activation; virus transcriptase; pdb; activation influenza ... See more keywords