The full activation mechanism of the adenosine A1 receptor revealed by GaMD and Su-GaMD simulations
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DOI: 10.1073/pnas.2203702119
Abstract: Significance Clarifying the recognition pathways of agonist and G protein to G protein–coupled receptor (GPCR) is essential to understand the signal transduction mechanism of GPCR. However, it is still challenging to simulate the full activation… read more here.
Keywords: activation mechanism; full activation; receptor; mechanism adenosine ... See more keywords