Molecular mechanism of anti‐adipogenic effect of vitexin in differentiating hMSCs
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DOI: 10.1002/ptr.7300
Abstract: In this study, we evaluated a detailed molecular mechanism of anti‐adipogenic activity of vitexin, apigenin flavone glucoside, present in germinated fenugreek seeds, in differentiating human mesenchymal stem cells (hMSCs). The lipid content of differentiated adipocytes… read more here.
Keywords: vitexin; anti adipogenic; mechanism anti; effect ... See more keywords
Ferroptosis, a novel pharmacological mechanism of anti-cancer drugs.
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DOI: 10.1016/j.canlet.2020.02.015
Abstract: Ferroptosis, a form of regulated cell death, is initiated by oxidative perturbations of the intracellular microenvironment, which is under the constitutive control of glutathione peroxidase 4 (GPX4). Ferrous iron (Fe2+) accumulation and lipid peroxidation are… read more here.
Keywords: novel pharmacological; mechanism anti; ferroptosis; ferroptosis novel ... See more keywords
On the mechanism of anti-CD39 immune checkpoint therapy
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DOI: 10.1136/jitc-2019-000186
Abstract: With the coming of age of cancer immunotherapy, the search for new therapeutic targets has led to the identification of immunosuppressive adenosine as an important regulator of antitumor immunity. This resulted in the development of… read more here.
Keywords: anti cd39; mechanism anti; therapy; cd39 immune ... See more keywords
Molecular Mechanism of Anti-Inflammatory Activities of a Novel Sulfated Galactofucan from Saccharina japonica
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DOI: 10.3390/md19080430
Abstract: Seaweed of Saccharina japonica is the most abundantly cultured brown seaweed in the world, and has been consumed in the food industry due to its nutrition and the unique properties of its polysaccharides. In this… read more here.
Keywords: anti inflammatory; mechanism anti; novel sulfated; sulfated galactofucan ... See more keywords