Mechanism for APOBEC3G catalytic exclusion of RNA and non-substrate DNA
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DOI: 10.1093/nar/gkz550
Abstract: Abstract The potent antiretroviral protein APOBEC3G (A3G) specifically targets and deaminates deoxycytidine nucleotides, generating deoxyuridine, in single stranded DNA (ssDNA) intermediates produced during HIV replication. A non-catalytic domain in A3G binds strongly to RNA, an… read more here.
Keywords: non substrate; mechanism apobec3g; rna; substrate dna ... See more keywords