Structural Insights into the Mechanism of Carbapenemase Activity of the OXA-48 β-Lactamase
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DOI: 10.1128/aac.01202-19
Abstract: Carbapenem-hydrolyzing class D carbapenemases (CHDLs) are enzymes that produce resistance to the last-resort carbapenem antibiotics, severely compromising the available therapeutic options for the treatment of life-threatening infections. A broad variety of CHDLs, including OXA-23, OXA-24/40,… read more here.
Keywords: baumannii; mechanism carbapenemase; oxa; carbapenemase activity ... See more keywords