Dissecting mechanism of coupled folding and binding of an intrinsically disordered protein by chemical synthesis of conformationally constrained analogues.
Sign Up to like & getrecommendations! Published in 2017 at "Chemical communications"
DOI: 10.1039/c7cc02276j
Abstract: Non-canonical α-methyl amino acids were incorporated at various sites in the sequence of intrinsically disordered activation domain from the p160 transcriptional co-activator (ACTR) to facilitate the formation of α-helical structures. Kinetic and thermodynamic data confirm… read more here.
Keywords: folding binding; mechanism; coupled folding; mechanism coupled ... See more keywords
Experimental Study of the Rock Mechanism under Coupled High Temperatures and Dynamic Loads
Sign Up to like & getrecommendations! Published in 2020 at "Advances in Civil Engineering"
DOI: 10.1155/2020/8866621
Abstract: With the development of modern society, geomaterials are widely used for infrastructure. These materials often experience dynamic loading and high temperature, which significantly influences the mechanical behaviour of the materials. This research focuses on the… read more here.
Keywords: high temperatures; rock mechanism; mechanism coupled; dynamic loads ... See more keywords