Molecular mechanism of fatty acid activation of FFAR1.
Sign Up to like & getrecommendations! Published in 2023 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2219569120
Abstract: FFAR1 is a G-protein-coupled receptor (GPCR) that responds to circulating free fatty acids to enhance glucose-stimulated insulin secretion and release of incretin hormones. Due to the glucose-lowering effect of FFAR1 activation, potent agonists for this… read more here.
Keywords: mechanism fatty; ffar1; receptor; fatty acid ... See more keywords
New Insights on the Mechanism of Fatty Acids as Buccal Permeation Enhancers
Sign Up to like & getrecommendations! Published in 2018 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics10040201
Abstract: Buccal mucosa has recently received much attention as a potential route for systemic delivery of drugs, including biologics and vaccines. The aim of this work was to gain insight into the mechanism of fatty acids… read more here.
Keywords: permeation enhancers; buccal permeation; mechanism fatty; fatty acids ... See more keywords