Regulation mechanism of ferroptosis and its research progress in tumor immunotherapy
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DOI: 10.3389/fmolb.2022.1045548
Abstract: Ferroptosis is a novel regulatory cell death, which is characterized by iron dependency and mainly caused by accumulation of intracellular lipid peroxides and reactive oxygen species. Ferroptosis plays an important role in the occurrence and… read more here.
Keywords: regulation mechanism; immunotherapy; mechanism ferroptosis; tumor immunotherapy ... See more keywords
The Mechanism of Ferroptosis and Applications in Tumor Treatment
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DOI: 10.3389/fphar.2020.01061
Abstract: Iron-dependent ferroptosis is a new form of cell death in recent years, which is driven by lipid peroxidation. The lethal lipid accumulation caused by glutathione depletion or inactivation of glutathione peroxidase 4 (GPX4) is characteristic… read more here.
Keywords: tumor treatment; ferroptosis applications; treatment; ferroptosis ... See more keywords
Editorial: Ferroptosis as new therapeutic targets in cancer: From molecular mechanisms to therapeutic opportunities
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DOI: 10.3389/fphar.2022.1019395
Abstract: Ferroptosis is a new form of programmed cell death characterized by iron-dependent accumulation of lipid reactive oxygen species (ROS). In the process of ferroptosis, excessive iron accumulation can trigger Fenton reaction in cells, induce massive… read more here.
Keywords: ferroptosis new; metabolism; editorial ferroptosis; mechanism ferroptosis ... See more keywords
Induction mechanism of ferroptosis: A novel therapeutic target in lung disease
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DOI: 10.3389/fphar.2022.1093244
Abstract: Ferroptosis is a newly discovered form of non-apoptotic regulatory cell death driven by iron-dependent lipid peroxidation. Ferroptosis significantly differs from other forms of cell death in terms of biochemistry, genetics, and morphology. Ferroptosis affects many… read more here.
Keywords: lung; mechanism ferroptosis; ferroptosis; lung disease ... See more keywords
Molecular regulatory mechanism of ferroptosis and its role in gastrointestinal oncology: Progress and updates
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DOI: 10.4251/wjgo.v14.i1.1
Abstract: Gastrointestinal (GI) tumors, including liver, pancreatic, gastric, and colorectal cancers, have a high incidence rate and low survival rate due to the lack of effective therapeutic methods and frequent relapses. Surgery and postoperative chemoradiotherapy have… read more here.
Keywords: ferroptosis; mechanism ferroptosis; gastrointestinal oncology; ferroptosis role ... See more keywords