Abstract 6686: The mechanism of gut microbiome-mediated immune activation on the clinical efficacy of PD-1 blocking treatment in solid tumors
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DOI: 10.1158/1538-7445.am2024-6686
Abstract: Gut microbiota is associated with antitumor efficacy of immune checkpoint blockade therapies, yet the mechanism is not largely understood. Here, we show that a novel bacterial strain of Ruminococcaceae isolated from the feces of patients… read more here.
Keywords: cd8 cells; microbiome mediated; gut microbiome; mechanism gut ... See more keywords
Immune mechanism of gut microbiota and its metabolites in the occurrence and development of cardiovascular diseases
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DOI: 10.3389/fmicb.2022.1034537
Abstract: The risk of cardiovascular disease (CVD) is associated with unusual changes in the human gut microbiota, most commonly coronary atherosclerotic heart disease, hypertension, and heart failure. Immune mechanisms maintain a dynamic balance between the gut… read more here.
Keywords: immune mechanism; microbiota metabolites; microbiota; gut microbiota ... See more keywords