Mechanism of histone deacetylases in cardiac hypertrophy and its therapeutic inhibitors
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cardiovascular Medicine"
DOI: 10.3389/fcvm.2022.931475
Abstract: Cardiac hypertrophy is a key process in cardiac remodeling development, leading to ventricle enlargement and heart failure. Recently, studies show the complicated relation between cardiac hypertrophy and epigenetic modification. Post-translational modification of histone is an… read more here.
Keywords: hypertrophy; histone deacetylases; cardiac hypertrophy; mechanism histone ... See more keywords
The role and mechanism of histone lactylation in health and diseases
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.949252
Abstract: Whether under anaerobic or aerobic conditions, glycolysis results in production of lactate. Increasing evidence suggests that lactate serves as a multifunctional signaling molecule that develops non-metabolic activities in addition to serving as a key metabolite… read more here.
Keywords: lactylation; histone lactylation; role mechanism; mechanism histone ... See more keywords