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Published in 2018 at "Nature Communications"
DOI: 10.1038/s41467-018-04214-8
Abstract: RIG-I is a viral RNA sensor that induces the production of type I interferon (IFN) in response to infection with a variety of viruses. Modification of RIG-I with K63-linked poly-ubiquitin chains, synthesised by TRIM25, is…
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Keywords:
trim25;
influenza;
recognition;
molecular mechanism ... See more keywords