Structural Insights into the Mechanism of a Nanobody That Stabilizes PAI-1 and Modulates Its Activity
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DOI: 10.3390/ijms21165859
Abstract: Plasminogen activator inhibitor-1 (PAI-1) is the main physiological inhibitor of tissue-type (tPA) and urokinase-type (uPA) plasminogen activators (PAs). Apart from being critically involved in fibrinolysis and wound healing, emerging evidence indicates that PAI-1 plays an… read more here.
Keywords: pai; nanobody; structural insights; mechanism nanobody ... See more keywords