Mechanism of Nickel(II)-Catalyzed C(2)–H Alkynylation of Indoles with Alkynyl Bromide
Sign Up to like & getrecommendations! Published in 2018 at "Organometallics"
DOI: 10.1021/acs.organomet.8b00177
Abstract: The nickel system (THF)2NiBr2/phen has recently been shown as an efficient catalyst for the C–H bond alkynylation of diverse heteroarenes with (triisopropylsilyl)alkynyl bromide via monodentate chelation assistance. Herein, we report an extensive mechanistic investigation for… read more here.
Keywords: alkynylation; alkynyl bromide; alkynylation indoles; phen ... See more keywords
Deciphering the mechanism of the nickel-catalyzed hydroalkoxylation reaction: A combined experimental and computational study
Sign Up to like & getrecommendations! Published in 2017 at "ACS Catalysis"
DOI: 10.1021/acscatal.7b00616
Abstract: ABSTRACT: The [Ni(COD)2]/P P-catalysed hydroalkoxylation of butadiene to form butenyl ethers is studied mechanistically, where P P = 1,4-bis(diphenylphosphino)butane (dppb) and 1,2-bis(diphenylphosphinomethyl)benzene (dppmb). Experimental studies suggest the intermediacy of [(P P)Ni(0)(butadiene)] and [(P P)Ni(II)(allyl)] intermediates… read more here.
Keywords: hydroalkoxylation; deciphering mechanism; hydroalkoxylation reaction; nickel catalyzed ... See more keywords