The protective mechanism of protein kinase R to inhibit neuronal ferroptosis in cerebral injury from subarachnoid hemorrhage
Sign Up to like & getrecommendations! Published in 2022 at "Brain and Behavior"
DOI: 10.1002/brb3.2722
Abstract: Purpose: To investigate the role and mechanism of protein kinase R (PKR) in subarachnoid hemorrhage (SAH)‐mediated ferroptosis. read more here.
Keywords: mechanism protein; subarachnoid hemorrhage; protein kinase; ferroptosis ... See more keywords
Mechanism of Protein Translocation by the Sec61 Translocon Complex.
Sign Up to like & getrecommendations! Published in 2022 at "Cold Spring Harbor perspectives in biology"
DOI: 10.1101/cshperspect.a041250
Abstract: The endoplasmic reticulum (ER) is a major site for protein synthesis, folding, and maturation in eukaryotic cells, responsible for production of secretory proteins and most integral membrane proteins. The universally conserved protein-conducting channel Sec61 complex… read more here.
Keywords: translocation sec61; sec61 translocon; protein translocation; mechanism protein ... See more keywords
Rate-limiting transport of positively charged arginine residues through the Sec-machinery is integral to the mechanism of protein secretion
Sign Up to like & getrecommendations! Published in 2022 at "eLife"
DOI: 10.7554/elife.77586
Abstract: Transport of proteins across and into membranes is a fundamental biological process with the vast majority being conducted by the ubiquitous Sec machinery. In bacteria, this is usually achieved when the SecY-complex engages the cytosolic… read more here.
Keywords: arginine; mechanism protein; transport; secretion ... See more keywords