Function and mechanism of the pyrin inflammasome
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DOI: 10.1002/eji.201746947
Abstract: Pyrin, encoded by the MEFV gene, is an intracellular pattern recognition receptor that assembles inflammasome complexes in response to pathogen infections. Mutations in the MEFV gene have been linked to autoinflammatory diseases such as familial… read more here.
Keywords: pyrin inflammasome; mechanism pyrin; function mechanism; immunology ... See more keywords