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Promoting the hippocampal PPARα expression participates in the antidepressant mechanism of reboxetine, a selective norepinephrine reuptake inhibitor

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0 Published in 2021 at "Behavioural Brain Research"

DOI: 10.1016/j.bbr.2021.113535

Abstract: Reboxetine, the first selective norepinephrine (NA) reuptake inhibitor used in the treatment of depression, mainly acts by binding to the NA transporter and blocking reuptake of extracellular NA. Recently, some other pharmacological targets beyond the… read more here.

Keywords: hippocampal ppar; reboxetine; antidepressant mechanism; mechanism reboxetine ... See more keywords