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Published in 2019 at "Drug discovery today"
DOI: 10.1016/j.drudis.2019.12.009
Abstract: Here, we introduce models at three levels (molecular level, cellular and omics level, and organ and system level) that study drug mechanism and safety in preclinical drug discovery. The models differ in both their scope…
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Keywords:
drug;
multiscale modelling;
mechanism safety;
drug mechanism ... See more keywords