Stepwise activation mechanism of the scramblase nhTMEM16 revealed by cryo-EM
Sign Up to like & getrecommendations! Published in 2019 at "eLife"
DOI: 10.7554/elife.44364
Abstract: Scramblases catalyze the movement of lipids between both leaflets of a bilayer. Whereas the X-ray structure of the protein nhTMEM16 has previously revealed the architecture of a Ca2+-dependent lipid scramblase, its regulation mechanism has remained… read more here.
Keywords: stepwise activation; scramblase; activation mechanism; mechanism ... See more keywords