A common mechanism of Sec61 translocon inhibition by small molecules
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DOI: 10.1101/2022.08.11.503542
Abstract: Itskanov and Wang et al. determined high-resolution structures of the human Sec61 channel inhibited by several structurally distinct small molecules and revealed the common inhibitor-binding site in Sec61 and molecular interactions in atomic detail. The… read more here.
Keywords: translocon inhibition; sec61 translocon; mechanism sec61; small molecules ... See more keywords