Epigenetic mechanism and target therapy of UHRF1 protein complex in malignancies
Sign Up to like & getrecommendations! Published in 2019 at "OncoTargets and therapy"
DOI: 10.2147/ott.s192234
Abstract: Ubiquitin-like with plant homeodomain and really interesting new gene finger domains 1 (UHRF1) functions as an epigenetic regulator recruiting PCNA, DNMT1, histone deacetylase 1, G9a, SuV39H, herpes virus-associated ubiquitin-specific protease, and Tat-interactive protein by multiple… read more here.
Keywords: mechanism target; uhrf1 protein; target therapy; protein ... See more keywords
PGC-1α in osteoarthritic chondrocytes: From mechanism to target of action
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2023.1169019
Abstract: Osteoarthritis (OA) is one of the most common degenerative joint diseases, often involving the entire joint. The degeneration of articular cartilage is an important feature of OA, and there is growing evidence that the mitochondrial… read more here.
Keywords: pgc osteoarthritic; chondrocytes mechanism; target action; mechanism target ... See more keywords