Motor control mechanism underlying pedaling skills: an analysis of bilateral coordination in the lower extremities
Sign Up to like & getrecommendations! Published in 2019 at "Artificial Life and Robotics"
DOI: 10.1007/s10015-019-00580-8
Abstract: In the field of competitive cycling, non-traumatic injuries arising from muscle fatigue have been recognized as a significant problem. Although muscle coordination of the lower extremities is key to achieve high efficiency in pedaling, only… read more here.
Keywords: coordination; muscle; coordination lower; mechanism underlying ... See more keywords
Mechanism Underlying Antitumor Effects of Sinomenine
Sign Up to like & getrecommendations! Published in 2019 at "Chinese Journal of Integrative Medicine"
DOI: 10.1007/s11655-019-3151-2
Abstract: Sinomenine (SIN) is a bioactive alkaloid compound extracted from a Chinese medicinal plant Sinomenium acutum. It is a multitarget antitumor natural substance. Various mechanisms have been proposed for the antitumor effects of SIN, such as… read more here.
Keywords: underlying antitumor; antitumor effects; mechanism underlying; sin ... See more keywords
Glucocorticoid receptor dysfunction orchestrates inflammasome effects on chronic obstructive pulmonary disease-induced depression: A potential mechanism underlying the cross talk between lung and brain
Sign Up to like & getrecommendations! Published in 2019 at "Brain, Behavior, and Immunity"
DOI: 10.1016/j.bbi.2019.02.001
Abstract: Depression is highly prevalent among patients with chronic obstructive pulmonary disease (COPD). However, depression with COPD comorbidity is often underdiagnosed and undertreated, and pathogenic research is also insufficient. In the present study, we characterised pulmonary… read more here.
Keywords: depression; mechanism; copd; mechanism underlying ... See more keywords
Capturing the Mechanism Underlying TOP mRNA Binding to LARP1.
Sign Up to like & getrecommendations! Published in 2019 at "Structure"
DOI: 10.1016/j.str.2019.10.006
Abstract: The RNA-binding protein La-related protein 1 (LARP1) plays a central role in ribosome biosynthesis. Its C-terminal DM15 region binds the 7-methylguanosine (m7G) cap and 5' terminal oligopyrimidine (TOP) motif characteristic of transcripts encoding ribosomal proteins… read more here.
Keywords: underlying top; capturing mechanism; mrna binding; mechanism ... See more keywords
Physiological mechanism underlying spikelet degeneration in rice
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Integrative Agriculture"
DOI: 10.1016/s2095-3119(18)61981-1
Abstract: Abstract The phenomenon of degenerated spikelets is very common in cereals, and considered as a serious physiological defect and a main constraint to grain production. Understanding the physiological mechanism in which spikelet degeneration occurs would… read more here.
Keywords: physiological mechanism; spikelet degeneration; degeneration; mechanism underlying ... See more keywords
Decoding Molecular Mechanism Underlying Human Olfactory Receptor OR8D1 Activation by Sotolone Enantiomers.
Sign Up to like & getrecommendations! Published in 2024 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.3c09142
Abstract: Sotolone, a chiral compound, plays an important role in the food industry. Herein, (R)-/(S)-sotolone were separated to determine their odor characteristics and thresholds in air (R-form: smoky, burned, herb, and green aroma, 0.0514 μg/m3; S-form:… read more here.
Keywords: sotolone; molecular mechanism; activation; decoding molecular ... See more keywords
Insights into the Molecular Mechanism Underlying tBID-Triggered Cell Death Probed by In Situ Raman Spectroscopy.
Sign Up to like & getrecommendations! Published in 2025 at "Nano letters"
DOI: 10.1021/acs.nanolett.5c04794
Abstract: The truncated BID (tBID) protein is crucially important for apoptosis, and recent studies have shown that it can directly trigger cell death. However, the underlying molecular mechanisms are poorly understood. Herein, we present the molecular… read more here.
Keywords: spectroscopy; tbid; raman spectroscopy; underlying tbid ... See more keywords
The mechanism underlying extrapulmonary complications of the coronavirus disease 2019 and its therapeutic implication
Sign Up to like & getrecommendations! Published in 2022 at "Signal Transduction and Targeted Therapy"
DOI: 10.1038/s41392-022-00907-1
Abstract: The coronavirus disease 2019 (COVID-19) is a highly transmissible disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that poses a major threat to global public health. Although COVID-19 primarily affects the respiratory… read more here.
Keywords: coronavirus disease; disease 2019; extrapulmonary complications; mechanism underlying ... See more keywords
Network pharmacology study of the mechanism underlying the therapeutic effect of Zhujing pill and its main component oleanolic acid against diabetic retinopathy
Sign Up to like & getrecommendations! Published in 2023 at "Bioscience Reports"
DOI: 10.1042/bsr20220893
Abstract: Abstract Diabetic retinopathy (DR) is the leading cause of blindness in the working population worldwide, with few effective drugs available for its treatment in the early stages. The Zhujing pill (ZJP) is well-established to enhance… read more here.
Keywords: pharmacology; mechanism underlying; zhujing pill; diabetic retinopathy ... See more keywords
Molecular mechanism underlying the TLR4 antagonistic and antiseptic activities of papiliocin, an insect innate immune response molecule
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2115669119
Abstract: Significance Similar to mammalian TLR4/MD-2, the Toll9/MD-2–like protein complex in the silkworm, Bombyx mori, acts as an innate pattern-recognition receptor that recognizes lipopolysaccharide (LPS) and induces LPS-stimulated expression of antimicrobial peptides such as cecropins. Here,… read more here.
Keywords: tlr4 antagonistic; molecular mechanism; mechanism underlying; immune response ... See more keywords
Persulfidation is the mechanism underlying sulfide-signaling of autophagy.
Sign Up to like & getrecommendations! Published in 2021 at "Autophagy"
DOI: 10.1080/15548627.2021.1936357
Abstract: In this commentary, we highlight the findings described in a recent paper regarding the mechanism of H2S regulation of macroautophagy/autophagy in mammalian cells and discuss the similarities/divergencies with plant cells. The main outcome is that… read more here.
Keywords: underlying sulfide; mechanism; persulfidation mechanism; sulfide signaling ... See more keywords