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Published in 2021 at "Clinical science"
DOI: 10.1042/cs20200301
Abstract: Anthracyclines are effective chemotherapeutic agents, commonly used in the treatment of a variety of hematologic malignancies and solid tumors. However, their use is associated with a significant risk of cardiovascular toxicities and may result in…
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Keywords:
mechanisms anthracycline;
molecular mechanisms;
anthracycline cardiovascular;
toxicity ... See more keywords
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Published in 2020 at "Frontiers in Cardiovascular Medicine"
DOI: 10.3389/fcvm.2020.00035
Abstract: Cardiac side effects are a major drawback of anticancer therapies, often requiring the use of low and less effective doses or even discontinuation of the drug. Among all the drugs known to cause severe cardiotoxicity…
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Keywords:
induced cardiotoxicity;
anthracycline induced;
cardiotoxicity;
mitochondrial dysfunction ... See more keywords