Articles with "mechanisms autophagy" as a keyword



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The Function and Mechanisms of Autophagy in Traumatic Brain Injury.

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Published in 2020 at "Advances in experimental medicine and biology"

DOI: 10.1007/978-981-15-4272-5_46

Abstract: Traumatic brain injury (TBI) is one of the most common causes of long-term disability and death worldwide. Autophagy is activated and autophagic flux is impaired following TBI. But the controversial roles and underlying mechanisms of… read more here.

Keywords: brain injury; traumatic brain; mechanisms autophagy; function mechanisms ... See more keywords
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Diverse mechanisms of autophagy dysregulation and their therapeutic implications: does the shoe fit?

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Published in 2018 at "Autophagy"

DOI: 10.1080/15548627.2018.1509609

Abstract: ABSTRACT In its third edition, the Vancouver Autophagy Symposium presented a platform for vibrant discussion on the differential roles of macroautophagy/autophagy in disease. This one-day symposium was held at the BC Cancer Research Centre in… read more here.

Keywords: autophagy dysregulation; mechanisms autophagy; disease; autophagy ... See more keywords
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Mechanisms of autophagy induction by sex steroids in bovine mammary epithelial cells.

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Published in 2017 at "Journal of molecular endocrinology"

DOI: 10.1530/jme-16-0247

Abstract: In dairy cattle, mammary gland involution serves to remodel the secretory tissue and occurs in a period of overlap between mammogenic stimulation caused by the next developing pregnancy and tissue regression induced by milk stasis.… read more here.

Keywords: epithelial cells; mammary epithelial; mechanisms autophagy; autophagy induction ... See more keywords
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Regulatory Mechanisms of Autophagy-Targeted Antimicrobial Therapeutics Against Mycobacterial Infection

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Published in 2021 at "Frontiers in Cellular and Infection Microbiology"

DOI: 10.3389/fcimb.2021.633360

Abstract: Mycobacterium tuberculosis (Mtb) is an intracellular pathogen causing human tuberculosis, an infectious disease that still remains as a global health problem. Autophagy, a lysosomal degradative process, has emerged as a critical pathway to restrict intracellular… read more here.

Keywords: mechanisms autophagy; regulatory mechanisms; infection; antimicrobial therapeutics ... See more keywords
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Brain-protective mechanisms of autophagy associated circRNAs: Kick starting self-cleaning mode in brain cells via circRNAs as a potential therapeutic approach for neurodegenerative diseases

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Published in 2023 at "Frontiers in Molecular Neuroscience"

DOI: 10.3389/fnmol.2022.1078441

Abstract: Altered autophagy is a hallmark of neurodegeneration but how autophagy is regulated in the brain and dysfunctional autophagy leads to neuronal death has remained cryptic. Being a key cellular waste-recycling and housekeeping system, autophagy is… read more here.

Keywords: mechanisms autophagy; brain; autophagy associated; brain protective ... See more keywords
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Molecular Mechanisms of Autophagy in Cancer Development, Progression, and Therapy

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Published in 2022 at "Biomedicines"

DOI: 10.3390/biomedicines10071596

Abstract: Autophagy is an evolutionarily conserved and tightly regulated process that plays an important role in maintaining cellular homeostasis. It involves regulation of various genes that function to degrade unnecessary or dysfunctional cellular components, and to… read more here.

Keywords: mechanisms autophagy; development; progression; autophagy cancer ... See more keywords