Mechanisms of bone remodeling and therapeutic strategies in chronic apical periodontitis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2022.908859
Abstract: Chronic periapical periodontitis (CAP) is a typical oral disease in which periodontal inflammation caused by an odontogenic infection eventually leads to bone loss. Uncontrolled infections often lead to extensive bone loss around the root tip,… read more here.
Keywords: mechanisms bone; repair; periodontitis; bone remodeling ... See more keywords
Therapeutics of Charcot neuroarthropathy and pharmacological mechanisms: A bone metabolism perspective
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2023.1160278
Abstract: Charcot neuroarthropathy (CN) is a chronic, destructive, and painless damage of the skeletal system that affects the life quality of patients. CN, with an unclear mechanism, is characterized with invasive destruction of bones and a… read more here.
Keywords: metabolism; bone metabolism; charcot neuroarthropathy; mechanisms bone ... See more keywords
Mechanisms of Bone Impairment in Sickle Bone Disease
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DOI: 10.3390/ijerph18041832
Abstract: Sickle bone disease (SBD) is a chronic and invalidating complication of Sickle cell disease (SCD), a multisystem autosomal recessive genetic disorder affecting millions of people worldwide. Mechanisms involved in SBD are not completely known, especially… read more here.
Keywords: sickle bone; mechanisms bone; bone; bone disease ... See more keywords
NEDD4 E3 Ligases: Functions and Mechanisms in Bone and Tooth
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DOI: 10.3390/ijms23179937
Abstract: Protein ubiquitination is a precisely controlled enzymatic cascade reaction belonging to the post-translational modification of proteins. In this process, E3 ligases catalyze the binding of ubiquitin (Ub) to protein substrates and define specificity. The neuronally… read more here.
Keywords: functions mechanisms; nedd4 subfamily; mechanisms bone; bone tooth ... See more keywords