Probing Biological Mechanisms with Chemical Tools.
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DOI: 10.1016/j.phrs.2020.104656
Abstract: Traditionally small molecules have mainly been used to inhibit biochemical activities of proteins, however such compounds can also be used to change the conformational energy landscape of proteins. Tool compounds that allosterically modulate protein conformations… read more here.
Keywords: chemical tools; probing biological; biological mechanisms; mechanisms chemical ... See more keywords