Molecular and cellular mechanisms of chemoresistance in pancreatic cancer.
Sign Up to like & getrecommendations! Published in 2018 at "Advances in biological regulation"
DOI: 10.1016/j.jbior.2017.11.007
Abstract: Pancreatic Ductal Adenocarcinoma (PDAC) is one of the most chemoresistant cancers, and current therapies targeting cancer-associated molecular pathways have not given satisfactory results, owing in part to rapid upregulation of alternative compensatory pathways. Most of… read more here.
Keywords: molecular cellular; cellular mechanisms; pancreatic cancer; cancer ... See more keywords
The molecular mechanisms of chemoresistance in cancers
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.19048
Abstract: Overcoming intrinsic and acquired drug resistance is a major challenge in treating cancer patients because chemoresistance causes recurrence, cancer dissemination and death. This review summarizes numerous molecular aspects of multi-resistance, including transporter pumps, oncogenes (EGFR,… read more here.
Keywords: chemoresistance; emt; chemoresistance cancers; cancer ... See more keywords
Novel mechanisms of chemoresistance by Fusobacterium nucleatum involve not so novel pathways of microRNAs and autophagy
Sign Up to like & getrecommendations! Published in 2018 at "Translational cancer research"
DOI: 10.21037/tcr.2017.12.20
Abstract: Colon cancer is the second leading cause of cancer death among both men and women in the United States. Even with available chemotherapies, a significant number of patients have recurrent disease, leading to the high… read more here.
Keywords: chemoresistance fusobacterium; novel mechanisms; fusobacterium nucleatum; cancer ... See more keywords
Early Mechanisms of Chemoresistance in Retinoblastoma
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DOI: 10.3390/cancers14194966
Abstract: Simple Summary Despite advances in chemotherapy for retinoblastoma over the past three decades, chemoresistance remains a major source of ocular and systemic morbidity. Here, we studied the early molecular mechanisms leading to carboplatin resistance. Carboplatin… read more here.
Keywords: retinoblastoma; early mechanisms; mechanisms leading; chemoresistance ... See more keywords