Articles with "mechanisms chk1" as a keyword



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Keeping RelApse in Chk: molecular mechanisms of Chk1 inhibitor resistance in lymphoma

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Published in 2022 at "Biochemical Journal"

DOI: 10.1042/bcj20220461

Abstract: Chk1 is a member of the DNA damage response pathway, whose loss leads to replication stress and genome instability. Because of its protective role against lethal levels of DNA replication stress, Chk1 has been studied… read more here.

Keywords: inhibitor resistance; mechanisms chk1; chk1; chk1 inhibitor ... See more keywords