Diverse Molecular Mechanisms Contribute to Differential Expression of Human Duplicated Genes
Sign Up to like & getrecommendations! Published in 2021 at "Molecular Biology and Evolution"
DOI: 10.1093/molbev/msab131
Abstract: Abstract Emerging evidence links genes within human-specific segmental duplications (HSDs) to traits and diseases unique to our species. Strikingly, despite being nearly identical by sequence (>98.5%), paralogous HSD genes are differentially expressed across human cell… read more here.
Keywords: diverse molecular; mechanisms contribute; expression; human ... See more keywords
Aging-Related Mechanisms Contribute to Corticosteroid Insensitivity in Elderly Asthma
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24076347
Abstract: Asthma in elderly populations is an increasing health problem that is accompanied by diminished lung function and frequent exacerbations. As potent anti-inflammatory drugs, corticosteroids are commonly used to reduce lung inflammation, improve lung function, and… read more here.
Keywords: lung function; lung; aging related; corticosteroid insensitivity ... See more keywords