Distinct molecular mechanisms control levels of synaptic F‐actin
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DOI: 10.1002/cbin.11226
Abstract: Polymerization of filamentous (F)‐actin at the neuronal synapse plays an important role in neuronal function. However, the regulatory mechanisms controlling the levels of synaptic actin remain incompletely understood. Here, I used established pharmacological blockers to… read more here.
Keywords: actin; distinct molecular; synaptic actin; levels synaptic ... See more keywords
Analysis of Genetically Diverse Macrophages Reveals Local and Domain-wide Mechanisms that Control Transcription Factor Binding and Function
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DOI: 10.1016/j.cell.2018.04.018
Abstract: Non-coding genetic variation is a major driver of phenotypic diversity and allows the investigation of mechanisms that control gene expression. Here, we systematically investigated the effects of >50 million variations from five strains of mice… read more here.
Keywords: transcription factor; factor binding; mechanisms control; transcription ... See more keywords
Topovectorial mechanisms control the juxtamembrane proteolytic processing of Nrf1 to remove its N‐terminal polypeptides during maturation of the CNC‐bZIP factor
Sign Up to like & getrecommendations! Published in 2018 at "Toxicology and Applied Pharmacology"
DOI: 10.1016/j.taap.2018.09.039
Abstract: &NA; The topobiological behaviour of Nrf1 dictates its post‐translational modification and its ability to transactivate target genes. Here, we have elucidated that topovectorial mechanisms control the juxtamembrane processing of Nrf1 on the cyto/nucleoplasmic side of… read more here.
Keywords: topovectorial mechanisms; juxtamembrane; mechanisms control; proteolytic processing ... See more keywords
Transfer of under-foot load and mechanisms of control in dart sports
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DOI: 10.1080/19424280.2017.1314331
Abstract: Bertsch, C., Unger, H., Winkelmann, W., & Rosenbaum, D. (2004). Evaluation of early walking patterns from plantar pressure distribution measurements. First year results of 42 children. Gait & Posture, 19(3), 235–242. Hallemans, A., D’Aout, K.,… read more here.
Keywords: load mechanisms; control dart; mechanisms control; foot load ... See more keywords
Timing mechanisms to control heart rhythm and initiate arrhythmias: roles for intracellular organelles, signalling pathways and subsarcolemmal Ca2+
Sign Up to like & getrecommendations! Published in 2023 at "Philosophical Transactions of the Royal Society B: Biological Sciences"
DOI: 10.1098/rstb.2022.0170
Abstract: Rhythms of electrical activity in all regions of the heart can be influenced by a variety of intracellular membrane bound organelles. This is true both for normal pacemaker activity and for abnormal rhythms including those… read more here.
Keywords: timing mechanisms; control heart; intracellular organelles; mechanisms control ... See more keywords