Region-specific mechanisms of corticosteroid-mediated inotropy in rat cardiomyocytes
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-68308-4
Abstract: Regional differences in ion channel activity in the heart control the sequence of repolarization and may contribute to differences in contraction. Corticosteroids such as aldosterone or corticosterone increase the L-type Ca2+ current (ICaL) in the… read more here.
Keywords: mechanisms corticosteroid; corticosteroid mediated; specific mechanisms; region specific ... See more keywords
Mechanisms of Corticosteroid Resistance in Type 17 Asthma.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of immunology"
DOI: 10.4049/jimmunol.2200288
Abstract: IL-17A plays an important role in the pathogenesis of asthma, particularly the neutrophilic corticosteroid (CS)-resistant subtype of asthma. Clinical studies suggest that a subset of asthma patients, i.e., Th17/IL-17A-mediated (type 17) CS-resistant neutrophilic asthma, may… read more here.
Keywords: lcn2 saa; mechanisms corticosteroid; asthma; type ... See more keywords