Articles with "mechanisms disease" as a keyword



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Mechanisms and disease consequences of nonalcoholic fatty liver disease

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Published in 2021 at "Cell"

DOI: 10.1016/j.cell.2021.04.015

Abstract: Nonalcoholic fatty liver disease (NAFLD) is the leading chronic liver disease worldwide. Its more advanced subtype, nonalcoholic steatohepatitis (NASH), connotes progressive liver injury that can lead to cirrhosis and hepatocellular carcinoma. Here we provide an… read more here.

Keywords: fatty liver; disease; mechanisms disease; disease consequences ... See more keywords
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Mechanisms of disease-associated SINE-VNTR-Alus.

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Published in 2022 at "Experimental biology and medicine"

DOI: 10.1177/15353702221082612

Abstract: SINE-VNTR-Alus (SVAs) are the youngest retrotransposon family in the human genome. Their ongoing mobilization has generated genetic variation within the human population. At least 24 insertions to date, detailed in this review, have been associated… read more here.

Keywords: vntr alus; mechanisms disease; disease; disease associated ... See more keywords
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Emerging Mechanisms and Disease Implications of Ferroptosis: Potential Applications of Natural Products

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Published in 2021 at "Frontiers in Cell and Developmental Biology"

DOI: 10.3389/fcell.2021.774957

Abstract: Ferroptosis, a newly discovered form of regulatory cell death (RCD), has been demonstrated to be distinct from other types of RCD, such as apoptosis, necroptosis, and autophagy. Ferroptosis is characterized by iron-dependent lipid peroxidation and… read more here.

Keywords: implications ferroptosis; emerging mechanisms; ferroptosis potential; disease implications ... See more keywords
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Mechanisms of Disease in Sjögren Syndrome—New Developments and Directions

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Published in 2020 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms21020650

Abstract: Sjögren Syndrome (SS) is an autoimmune disease that affects the exocrine glands, mainly salivary and lacrimal glands [...]. read more here.

Keywords: gren syndrome; disease gren; syndrome new; mechanisms disease ... See more keywords
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Waldenström Macroglobulinemia: Mechanisms of Disease Progression and Current Therapies

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Published in 2022 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms231911145

Abstract: Waldenström macroglobulinemia is an indolent, B-cell lymphoma without a known cure. The bone marrow microenvironment and cytokines both play key roles in Waldenström macroglobulinemia (WM) tumor progression. Only one FDA-approved drug exists for the treatment… read more here.

Keywords: waldenstr macroglobulinemia; progression; macroglobulinemia mechanisms; mechanisms disease ... See more keywords