A Comprehensive Insight into the Mechanisms of Dopamine in Disrupting Aβ Protofibrils and Inhibiting Aβ Aggregation.
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DOI: 10.1021/acschemneuro.1c00306
Abstract: Fibrillary aggregates of amyloid-β (Aβ) are the pathological hallmark of Alzheimer's disease (AD). Clearing Aβ deposition or inhibiting Aβ aggregation is a promising approach to treat AD. Experimental studies reported that dopamine (DA), an important… read more here.
Keywords: aggregation; inhibiting aggregation; insight mechanisms; dopamine disrupting ... See more keywords