Tremella polysaccharide: The molecular mechanisms of its drug action.
Sign Up to like & getrecommendations! Published in 2019 at "Progress in molecular biology and translational science"
DOI: 10.1016/bs.pmbts.2019.03.002
Abstract: Tremella fuciformis is an edible medicinal mushroom well known as "Yiner" or "Baimuer" in China and has been used as a Chinese herb for many years. T. fuciformis polysaccharide (TFPS) has been identified as a… read more here.
Keywords: polysaccharide molecular; molecular mechanisms; drug; mechanisms drug ... See more keywords
Single cell mass spectrometry studies reveal metabolomic features and potential mechanisms of drug-resistant cancer cell lines.
Sign Up to like & getrecommendations! Published in 2022 at "Analytica chimica acta"
DOI: 10.1016/j.aca.2022.339761
Abstract: Irinotecan (Iri) is a key drug to treat metastatic colorectal cancer, but its clinical activity is often limited by de novo and acquired drug resistance. Studying the underlying mechanisms of drug resistance is necessary for… read more here.
Keywords: mechanisms drug; cancer; cell; iri resistant ... See more keywords
Mechanisms of drug resistance of pancreatic ductal adenocarcinoma at different levels
Sign Up to like & getrecommendations! Published in 2020 at "Bioscience Reports"
DOI: 10.1042/bsr20200401
Abstract: Abstract Pancreatic ductal adenocarcinoma (PDAC) is the fourth leading cause of cancer-related death worldwide, and the mortality of patients with PDAC has not significantly decreased over the last few decades. Novel strategies exhibiting promising effects… read more here.
Keywords: drug resistance; ductal adenocarcinoma; pancreatic ductal; mechanisms drug ... See more keywords
Mechanisms of Drug-Induced Interstitial Nephritis.
Sign Up to like & getrecommendations! Published in 2017 at "Advances in chronic kidney disease"
DOI: 10.1053/j.ackd.2016.11.004
Abstract: Drug-induced acute interstitial nephritis (DI-AIN) is a drug hypersensitivity reaction (DHR) that manifests 7 to 10 days after exposure to the culprit drug. DHRs account for fewer than 15% of reported adverse drug reactions. The kidneys… read more here.
Keywords: interstitial nephritis; drug; drug induced; hypersensitivity ... See more keywords
Mechanisms of drug resistance in HCC.
Sign Up to like & getrecommendations! Published in 2023 at "Hepatology"
DOI: 10.1097/hep.0000000000000237
Abstract: HCC comprises ∼80% of primary liver cancer. HCC is the only major cancer for which death rates have not improved over the last 10 years. Most patients are diagnosed with advanced disease when surgical and… read more here.
Keywords: hcc; mechanisms drug; resistance hcc; resistance ... See more keywords
Exploring the underlying mechanisms of drug‐induced impulse control disorders: a pharmacovigilance‐pharmacodynamic study
Sign Up to like & getrecommendations! Published in 2022 at "Psychiatry and Clinical Neurosciences"
DOI: 10.1111/pcn.13511
Abstract: Impulse control disorders (e.g. pathological gambling, hypersexuality) may develop as adverse reactions to drugs. Pathogenetic hypotheses have mainly focused on D3‐receptor agonism, and switching to alternatives with different pharmacologic mechanisms represents a common management strategy.… read more here.
Keywords: exploring underlying; control disorders; impulse control; mechanisms drug ... See more keywords
Mechanisms of drug resistance in acute myeloid leukemia
Sign Up to like & getrecommendations! Published in 2019 at "OncoTargets and therapy"
DOI: 10.2147/ott.s191621
Abstract: Acute myeloid leukemia (AML) is a kind of malignant hematopoietic system disease characterized by abnormal proliferation, poor cell differentiation, and infiltration of bone marrow, peripheral blood, or other tissues. To date, the first-line treatment of… read more here.
Keywords: leukemia; acute myeloid; mechanisms drug; resistance ... See more keywords
mRNA Vaccine Era—Mechanisms, Drug Platform and Clinical Prospection
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms21186582
Abstract: Messenger ribonucleic acid (mRNA)-based drugs, notably mRNA vaccines, have been widely proven as a promising treatment strategy in immune therapeutics. The extraordinary advantages associated with mRNA vaccines, including their high efficacy, a relatively low severity… read more here.
Keywords: mrna vaccine; mrna vaccines; vaccine era; mechanisms drug ... See more keywords
Molecular Mechanisms of Drug Resistance in Staphylococcus aureus
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23158088
Abstract: This paper discusses the mechanisms of S. aureus drug resistance including: (1) introduction. (2) resistance to beta-lactam antibiotics, with particular emphasis on the mec genes found in the Staphylococcaceae family, the structure and occurrence of… read more here.
Keywords: molecular mechanisms; mechanisms drug; resistance; resistance staphylococcus ... See more keywords