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Published in 2025 at "Biochemical Society Transactions"
DOI: 10.1042/bst20240859
Abstract: Interferon-stimulated gene 15 (ISG15) is a ubiquitin-like protein and, as such, acts as a post-translational modifier that plays a critical role during bacterial and viral infections after interferon (IFN) production. As part of the innate…
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Keywords:
isg15 deconjugation;
mechanisms functions;
human viral;
functions isg15 ... See more keywords
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Published in 2024 at "Philosophical Transactions of the Royal Society B: Biological Sciences"
DOI: 10.1098/rstb.2023.0411
Abstract: The concept of episodic memory (EM) faces significant challenges by two claims: EM might not be a distinct memory system, and EM might be an epiphenomenon of a more general capacity for mental time travel…
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Keywords:
system;
mechanisms functions;
memory;
distinct mechanisms ... See more keywords
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Published in 2022 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2022/2501279
Abstract: Eukaryotic cells can initiate several distinct self-destruction mechanisms to display essential roles for the homeostasis maintenance, development, and survival of an organism. Pyroptosis, a key response mode in innate immunity, also referred to as caspase-1-dependent…
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Keywords:
infectious diseases;
pyroptosis;
functions pyroptosis;
focus mechanisms ... See more keywords
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Published in 2020 at "PLoS Genetics"
DOI: 10.1371/journal.pgen.1008709
Abstract: As the maternal–foetal interface, the placenta is essential for the establishment and progression of healthy pregnancy, regulating both foetal growth and maternal adaptation to pregnancy. The evolution and functional importance of genomic imprinting are inextricably…
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Keywords:
imprinting emerging;
emerging mechanisms;
placental imprinting;
mechanisms functions ... See more keywords
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Published in 2024 at "Biological Chemistry"
DOI: 10.1515/hsz-2024-0038
Abstract: Abstract Posttranslational modifications (PTMs) can modulate the activity, localization and interactions of proteins and (re)define their biological function. Understanding how changing environments can alter cellular processes thus requires detailed knowledge about the dynamics of PTMs…
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Keywords:
protein persulfidation;
mechanisms functions;
persulfidation;
protein ... See more keywords
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Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.864191
Abstract: Lamins are the ancient type V intermediate filament proteins contributing to diverse biological functions, such as the maintenance of nuclear morphology, stabilization of chromatin architecture, regulation of cell cycle progression, regulation of spatial-temporal gene expressions,…
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Keywords:
post translational;
lamins mechanisms;
translational modification;
chromatin ... See more keywords
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Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.967875
Abstract: In multicellular organisms, cells must continuously exchange messages with the right meaning, intensity, and duration. Most of these messages are delivered through cognate interactions between membrane and secretory proteins. Their conformational maturation is assisted by…
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Keywords:
selective secretion;
proteins mechanisms;
kdel bearing;
mechanisms functions ... See more keywords
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Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2023.1065181
Abstract: Inflammasomes are multiprotein complexes, which are assembled in response to a diverse range of exogenous pathogens and endogenous danger signals, leading to produce pro-inflammatory cytokines and induce pyroptotic cell death. Inflammasome components have been identified…
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Keywords:
inflammasome complexes;
functions inflammasome;
teleost fish;
emerging mechanisms ... See more keywords
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Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.794448
Abstract: Male infertility is a major and growing health problem with an estimated global prevalence of 4.2%. The current therapy is limited by the unknown etiology of MI, emphasizing the critical requirement forward to a more…
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Keywords:
components mechanisms;
core;
medicine;
pharmacology ... See more keywords
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Published in 2024 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms25137398
Abstract: The oral detection of sugars relies on two types of receptor systems. The first is the G-protein-coupled receptor TAS1R2/TAS1R3. When activated, this receptor triggers a downstream signaling cascade involving gustducin, phospholipase Cβ2 (PLCβ2), and transient…
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Keywords:
receptor;
mechanisms functions;
extraoral organs;
receptor systems ... See more keywords
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Published in 2022 at "eLife"
DOI: 10.7554/elife.83044
Abstract: Gamma oscillations are believed to underlie cognitive processes by shaping the formation of transient neuronal partnerships on a millisecond scale. These oscillations are coupled to the phase of breathing cycles in several brain areas, possibly…
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Keywords:
respiration driven;
functions respiration;
olfactory cortex;
gamma oscillations ... See more keywords