Using genetically encoded heme sensors to probe the mechanisms of heme uptake and homeostasis in Candida albicans
Sign Up to like & getrecommendations! Published in 2020 at "Cellular Microbiology"
DOI: 10.1111/cmi.13282
Abstract: Candida albicans is a major fungal pathogen that can utilise hemin and haemoglobin as iron sources in the iron‐scarce host environment. While C. albicans is a heme prototroph, we show here that it can also… read more here.
Keywords: heme; genetically encoded; mechanisms heme; candida albicans ... See more keywords
Evaluation of the mechanisms of heme-induced tissue factor activation: Contribution of innate immune pathways
Sign Up to like & getrecommendations! Published in 2022 at "Experimental Biology and Medicine"
DOI: 10.1177/15353702221106475
Abstract: Hemolytic diseases such as Sickle Cell Disease (SCD) are characterized by a natural propensity for both arterial and venous thrombosis. The ability of heme to induce tissue factor (TF) activation has been shown both in… read more here.
Keywords: heme; factor activation; tissue factor; mechanisms heme ... See more keywords