Mechanisms of kinetic stabilization by the drugs paclitaxel and vinblastine
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Biology of the Cell"
DOI: 10.1091/mbc.e16-08-0567
Abstract: Chemotherapeutic agents that target microtubule dynamics promote a universal phenotype of kinetic stabilization. Integrated computational modeling and fluorescence microscopy identify the fundamental kinetic and thermodynamic mechanisms that result in kinetic stabilization, specifically by the drugs… read more here.
Keywords: stabilization; kinetic stabilization; drugs paclitaxel; mechanisms kinetic ... See more keywords