Mechanisms Linking Mitochondrial Dysfunction and Proteostasis Failure.
Sign Up to like & getrecommendations! Published in 2020 at "Trends in cell biology"
DOI: 10.1016/j.tcb.2020.01.008
Abstract: Maintaining cellular protein homeostasis (proteostasis) is an essential task for all eukaryotes. Proteostasis failure worsens with aging and is considered a cause of and a therapeutic target for age-related diseases including neurodegenerative disorders. The cellular… read more here.
Keywords: mechanisms linking; mitochondrial dysfunction; proteostasis; proteostasis failure ... See more keywords
Mechanisms linking hypertriglyceridemia to acute pancreatitis
Sign Up to like & getrecommendations! Published in 2023 at "Acta Physiologica"
DOI: 10.1111/apha.13916
Abstract: Hypertriglyceridemia (HTG) is a metabolic disorder, defined when serum or plasma triglyceride concentration (seTG) is >1.7 mM. HTG can be categorized as mild to very severe groups based on the seTG value. The risk of acute… read more here.
Keywords: acute pancreatitis; htg; mechanisms linking; linking hypertriglyceridemia ... See more keywords
Bioenergetic Mechanisms Linking V˙O2 Kinetics and Exercise Tolerance
Sign Up to like & getrecommendations! Published in 2021 at "Exercise and Sport Sciences Reviews"
DOI: 10.1249/jes.0000000000000267
Abstract: V˙O2 kinetics determine exercise tolerance by mediating the power output at which muscle metabolite accumulation exceeds a “critical threshold.” We hypothesize that the V˙O2 time constant (τV˙O2) determines exercise tolerance by defining the power output… read more here.
Keywords: exercise tolerance; mechanisms linking; bioenergetic mechanisms; linking kinetics ... See more keywords
Mechanisms Linking Hyperuricemia to Increased Cardiovascular Risk
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Korean Medical Science"
DOI: 10.3346/jkms.2019.34.e247
Abstract: Park et al.4 observed a significant correlation of serum homocysteine levels with carotid intima-media thickness or renal impairments among hyperuricemic patients. The finding is not surprising based on the previous report that both metabolic syndrome… read more here.
Keywords: risk; mechanisms linking; hyperuricemia increased; linking hyperuricemia ... See more keywords
Gut Mechanisms Linking Intestinal Sweet Sensing to Glycemic Control
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2018.00741
Abstract: Sensing nutrients within the gastrointestinal tract engages the enteroendocrine cell system to signal within the mucosa, to intrinsic and extrinsic nerve pathways, and the circulation. This signaling provides powerful feedback from the intestine to slow… read more here.
Keywords: mechanisms linking; linking intestinal; control; gut mechanisms ... See more keywords
Molecular Mechanisms Linking Risk Factors to Cholangiocarcinoma Development
Sign Up to like & getrecommendations! Published in 2022 at "Cancers"
DOI: 10.3390/cancers14061442
Abstract: Simple Summary Cholangiocarcinoma is the second most frequent primary liver tumor in humans. In this review, we report current findings on the mechanisms linking well-known risk factors to this cancer. These pathways may be in… read more here.
Keywords: risk; factors cholangiocarcinoma; molecular mechanisms; linking risk ... See more keywords