Structural and biochemical mechanisms of NLRP1 inhibition by DPP9
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DOI: 10.1038/s41586-021-03320-w
Abstract: Nucleotide-binding domain, leucine-rich repeat receptors (NLRs) mediate innate immunity by forming inflammasomes. Activation of the NLR protein NLRP1 requires autocleavage within its function-to-find domain (FIIND)1–7. In resting cells, the dipeptidyl peptidases DPP8 and DPP9 interact… read more here.
Keywords: mechanisms nlrp1; structural biochemical; biochemical mechanisms; dpp9 ... See more keywords