Mechanisms of nuclear content loading to exosomes
Sign Up to like & getrecommendations! Published in 2019 at "Science Advances"
DOI: 10.1126/sciadv.aax8849
Abstract: Nuclear-derived exosomes generated by micronuclear collapse provide an accurate snapshot of genomic features in ovarian cancer. Exosome cargoes are highly varied and include proteins, small RNAs, and genomic DNA (gDNA). The presence of gDNA suggests… read more here.
Keywords: content loading; mechanisms nuclear; loading exosomes; cancer ... See more keywords
Components and Mechanisms of Nuclear Mechanotransduction.
Sign Up to like & getrecommendations! Published in 2021 at "Annual review of cell and developmental biology"
DOI: 10.1146/annurev-cellbio-120319-030049
Abstract: The cell nucleus is best known as the container of the genome. Its envelope provides a barrier for passive macromolecule diffusion, which enhances the control of gene expression. As its largest and stiffest organelle, the… read more here.
Keywords: nuclear mechanotransduction; mechanisms nuclear; components mechanisms; biology ... See more keywords