Mechanisms of PARP inhibitor resistance in cancer and insights into the DNA damage response
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DOI: 10.1186/s13073-018-0612-8
Abstract: Editorial summaryInhibitors of poly(ADP-ribose) polymerase (PARPi) have entered the clinic for the treatment of patients with cancers that lack homology-directed DNA repair, but drug resistance remains a clinical hurdle. Recent advances in the identification of… read more here.
Keywords: mechanisms parp; parp inhibitor; resistance; resistance cancer ... See more keywords