Mechanisms that promote the evolution of cross-reactive antibodies upon vaccination with designed influenza immunogens
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DOI: 10.1101/2022.12.02.518838
Abstract: SUMMARY Immunogens that elicit broadly neutralizing antibodies targeting the conserved receptor-binding site (RBS) on influenza hemagglutinin (HA) may serve as a universal influenza vaccine candidate. Here, we developed a computational model to interrogate antibody evolution… read more here.
Keywords: promote evolution; vaccination; cross reactive; mechanisms promote ... See more keywords