Identification of pharmacodynamic biomarkers and common molecular mechanisms of response to genotoxic agents in cancer cell lines
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DOI: 10.1007/s00280-019-03898-z
Abstract: Genotoxic agents (GAs) including cisplatin, doxorubicin, gemcitabine, and topotecan are often used in cancer treatment. However, the response to GAs is variable among patients and predictive biomarkers are inadequate to select patients for treatment. Accurate… read more here.
Keywords: genotoxic agents; response; cell lines; mechanisms response ... See more keywords